Within the mandible it usually develops in the posterior area, whereas in the case of the maxilla it occurs in the area of the front teeth 6. Peripheral ossifying fibroma has to be differentiated from traumatic fibroma, peripheral giant cell granuloma, pyogenic granuloma, and peripheral odontogenic fibroma. It is sometimes also called peripheral cementoossifying fibroma but is quite distinct from the central cementoossifying tumour of bone. Peripheral ossifying fibroma, also known as ossifying fibrous epulis, is a gingival nodule which is composed of a cellular fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralised products, which consists of bone, cementumlike tissue, or a dystrophic calcification. The differences between the two lesions are discussed, and com parisons are. Peripheral odontogenic fibroma is an uncommon benign tumour of the gum and is the equivalent of a central odontogenic fibroma occuring outside of bone. Granular cell peripheral odontogenic fibroma lownie 1976.
He also suggested that the name peripheral ossifying fibroma should be retained for this lesion. However, to our knowledge, there is no information concerning peripheral odontogenic fibroma in the african pygmy hedgehog. American journal of pharmacology and pharmacotherapeutics. The present report appears to be the first in which external tooth resorption in the coronal and cervical regions has been associated with a peripheral odontogenic fibroma. Peripheral ossifying fibroma a clinical and histological. In the present case, a treatment option for the removal of odontogenic peripheral fibroma is presented. Who classification of head and neck tumours, 4th edition. These granular cells are similar to those previously described in the granular cell myoblastoma, congenital epulis and the granular cell ameloblastic fibroma. Peripheral odontogenic fibroma in the mandibular gingiva. The purpose of this study was to define the clinical and histopathologic spectrum of podf and to investigate its recurrence rate and variables associated with its recurrence. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization. Peripheral odontogenic fibroma is an uncommon neoplasm that is believed to arise from odontogenic epithelial rests in periodontal ligament or attached gingiva itself. It appears to be far more common than its intraosseous counterpart, central odontogenic fibroma. Interrelationship between pyogenic granuloma and peripheral.
Peripheral odontogenic fibroma is often misdiagnosed as fibrous epulis and easily confused. Odontogenic fibroma definition of odontogenic fibroma by. It commonly mimics other peripheral exophytic lesions like pyogenic granuloma, peripheral. This is the reason we might recommend either an incisional or excisional biopsy to first obtain the correct. Jun 30, 2017 peripheral odontogenic fibroma is considered to be a rare condition although, as shown in table 1, there have been 422 cases reported in the literature to date. A case of peripheral odontogenic fibroma with its clinicopathologic findings are documented here. Peripheral odontogenic ossifying fibroma registered. Peripheral odontogenic fibroma pof is defined as a benign neoplasm of the jaws of odontogenic ectomesenchymal origin. Pdf peripheral odontogenic fibroma pof is a rare odontogenic tumor. Presence of hypocellular stroma containing inactive odontogenic epithelium and dysplastic dentin or cementum like material is found in peripheral odontogenic fibroma. It can be found on either the inner lingualpalatal or outer labialbuccal surface of the gum. Odontogenic fibroma of, a rare odontogenic tumor of mesodermal origin, has been thought to originate from either dental follicle, periodontal ligament, or dental papilla 1. Peripheral odontogenic tumor is one of the rare forms of benign gingival enlargements.
Peripheral odontogenic fibroma is the preferred name of a help. Ossifying epulis, fibromatous epulis, and fibroosseous epulis are all terms that have been used in the past. The peripheral odontogenic fibroma is an uncommon gingival mass. Peripheral odontogenic fibroma who type is an uncommon neoplasm that is believed to arise from odontogenic epithelial rests in periodontal ligament or attached gingiva itself. Clinical features of peripheral odontogenic fibroma. Females are more commonly affected than males, and anterior maxilla is the most prevalent location of. American journal of pharmacology and pharmacotherapeutics peripheral ossifying fibroma mimicking pyogenic granuloma a case report sivakumarashankari, gaurav, jayanthi k and kamala r. There was considerable confusion in the terminology used in the literature until it was distinguished from peripheral odontogenic fibroma in a recent who classification. Since the present case showed a multilocular radiolucency with partially illdefined border between the right mandibular condyle and the distal root of the right mandibular third molar.
Granular cell peripheral odontogenic fibroma lownie. Shetty memorial institute of dental sciences, mangalore. Sep 03, 2010 at one time, the terms peripheral ossifying fibroma and peripheral odontogenic fibroma were used quite interchangeably till gardener published a clarification in terminology. Comparison between the peripheral ossifying fibroma and. Multifocal peripheral odontogenic fibroma kamal r, palaskar s. The ccot and the keratocystic odontogenic tumor may also occur in gingiva at any age, but keratocystic odontogenic tumor usually present in older adults, whereas other rare peripheral odontogenic tumors. Peripheral lesions have higher prediliction in 2nd and 4th decades of life, occurring commonly in the anterior mandibular gingival region than maxilla 1. Obstruction of the eruption pathway by peripheral odontogenic fibroma. Peripheral ossifying fibroma pof is a nonneoplastic enlargement of gingiva that is classified as a reactive hyperplastic inflammatory lesion. What is peripheral ossifying fibroma peripheral ossifying fibroma is a benign swelling of the gum, most commonly seen in teenagers and young adults.
It must be distinguished from the more common peripheral ossifying fibroma. Recurrent peripheral odontogenic fibroma of the attached. The peripheral odontogenic fibroma is a tumor of the oral submucosa, or periodontal ligament caused by chronic irritation, local trauma, dental calculus foreign agents or certain agents that may transform the connective tissue of the mucous membranes in fibrous tissue. It has also been reported that they commonly occur in association with an impacted tooth. The clinical and histological data of 51 cases of peripheral ossifying fibroma were retrieved from the records of department of oral pathology and microbiology, a. They can be further subclassified as peripheral odontogenic fibromas and acanthomatus ameloblastomas. Journal of oral and maxillofacial pathology jomfp is the official publication of the indian association of oral and maxillofacial pathology, india. The peripheral odontogenic fibroma epulis is a clinical term referring to a slow growing, localized, exophytic mass on the gingiva resulting from chronic irritation. To present the clinical presence, histopathological features, and management of a rare peripheral odontogenic fibroma pof case. It commonly mimics other peripheral exophytic lesions like pyogenic granuloma. It is derived from cells of the periodontal ligament and is usually classified as a reactive hyperplasia but sometimes as a benign neoplasm. We also suggest that the term who type be used to distinguish peripheral odontogenic fibromas from the peripheral ossifying fibroma with which they have often. Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme.
Peripheral odontogenic fibroma is a benign tumour that arises from the periodontal ligament. However, certain authors have stated that peripheral ossifying fibroma is a variant of central ossifying fibroma and, therefore, a neoplastic process. It can be confused with the peripheral ossifying fibroma. Peripheral odontogenic fibroma was earlier quite commonly confused with peripheral ossifying fibroma, until who classification 1992, classified it under odontogenic tumours. Goldschmidt department of pathobiology, laboratory of pathology, university of pennsylvania school of veterinary medicine, 3 800 spruce street, philadelphia, pa abstract. The peripheral odontogenic fibroma is a relatively rare, benign, unencapsulated and gingival mass of fibrous connective tissue, considered to be the extraosseous counterpart of the central odontogenic fibroma. Peripheral odontogenic fibroma pof is a rare odontogenic tumor. Odontogenic fibroma odonf is a mesenchymal odontogenic tumor 1.
Peripheral ossifying fibroma pof is a reactive gingival overgrowth which is relatively uncommon in nature. A peripheral odontogenic fibroma presents as a slow growing firm lump on the gum. Odontogenic tumors mainly occur as intraosseous growths but sometimes may present in a peripheral location on the gingiva where they are referred to as. Odontogenic tumors mainly occur as intraosseous growths but sometimes may present in a peripheral location on the gingiva where they are referred to as peripheral odontogenic tumors pots which are a rare entity, the most common of them being the peripheral odontogenic fibroma that is an otherwise uncommon, slowly growing, benign. According to the literature, the most common tumors of. It is considered an uncommon neoplasm that affects patients in a wide age group, with certain predominance in girls and women. Pofs comprises of, one or more mineralized tissues, including bone, cementum like material or dystrophic calcification, within a matrix of cellular fibroblastic tissue 2. At animal dentistry and oral surgery specialists, llc, we diagnose first to treat optimally correctly. Peripheral odontogenic fibroma was earlier quite commonly confused with peripheral ossifying fibroma, until who classification 1992, classified it under.
A case of a peripheral odontogenic fibroma which contained aggregates of large granular cells is reported. Here, a case of central odontogenic fibroma in a 17yearold male is reported. Peripheral odontogenic fibroma is a benign, slowgrowing, exophytic lesion occurring on the gingiva. The tumours occurring in the oral cavity may be of odontogenic or non odontogenic in origin. Peripheral odontogenic fibroma is considered to be a rare condition although, as shown in table 1, there have been 422 cases reported in the literature to date. Peripheral odontogenic fibroma is often misdiagnosed as fibrous epulis and easily confused with peripheral osteofibroma. Of develops within the mandible six times more frequently than within the maxilla. In the past, pof was mixed with peripheral ossifying fibroma due to the similarity of clinical and histologic findings. The peripheral ossifying fibroma pof is a relatively uncommon reactive lesion of the gingiva, associated with mineralization and derived from the periodontal ligament cells 6. Oral masses can be very serious or malignant, while others are much less serious, or benign. A case is reported of a lesion that recurred in the attached gingiva following initial excision. Peripheral odontogenic fibroma is an uncommon neoplasm that is believed to arise from.
The patient is a 51yearold white female maintenance patient who has not had a dental appointment in over two years. Currently, localized reactive hyperplastic lesions of the gingiva have been classified as focal fibrous hyperplasia, pg, peripheral ossifying fibroma. Peripheral odontogenic fibromacase report sciencedirect. Layfield ll, shopper tp, weir jc 1995 a diagnostic survey of biopsied gingival lesions. Initial periodontal treatment was delivered and the patient was informed about proper oral hygiene. Peripheral odontogenic fibroma formerly known as fibromatous and ossifying epulis is a benign, often slowgrowing tumor that arises from periodontal structures.
Pdf obstruction of the eruption pathway by peripheral. This paper presents a report of peripheral odontogenic fibroma of maxilla in a 61 year old male which clinically presented as a slow growing, firm, solitary mass in the gingiva in relation to right upper canine and premolar region. While the former one is a commonly found reactive lesion with wellformed bone, numerous giant cells and only rarely, if present, odontogenic epithelial rests, the latter. The podf is a benign, slowgrowing, exophytic lesion. Surgical resection of peripheral odontogenic fibromas in. Peripheral odontogenic fibromas have been extensively reported in a variety of domestic mammals and humans 1116. P eripheral odontogenic fibroma is an uncommon, benign, unencapsulated, exophytic gingival mass of fibrous connective tissue covered with a surface epithelium. The present article is a case report related to peripheral ossifying fibroma in a year male who reported with a painless growth in the mandibular. In contrast to the peripheral ossifying fibroma, the peripheral odontogenic fibroma is a rare lesion. Odontogenic tumours occur commonly as an intraosseous counterpart but may also present in the peripheral location on the gingiva and in such cases they are. The peripheral odontogenic fibroma podf is a rare benign neoplasm of odontogenic origin with limited data on recurrence. On presentation, the area of concern typically is a firm, pink, smooth swelling of the gingiva and normally seen as gingival hyperplasia. It may also contain dysplastic dentin, cementumlike calcifications, and bony trabeculae. Peripheral odontogenic fibroma epulis is the most common oral mass found in dogs.
Gingival enlargement is most common occurring entity in oral cavity. Peripheral ossifying fibroma europe pmc article europe. Fibro osseous lesions of the jaw continue to present problems in diagnosis and classification to clinicians and pathologists. They present as firm, smooth swellings of the gingiva and are normally indistinguishable from gingival hyperplasia. Odontogenic epithelium and mineralized material may be found in the mass. Who classification of head and neck tumours, 4th edition, 2017 odontogenic fibroma. Peripheral ossifying fibroma pof represents a rare separate entity of reactive benign lesion of connective tissue origin, not being the soft tissue counterpart of central ossifying fibroma.
Peripheral odontogenic fibroma synonyms, peripheral odontogenic fibroma pronunciation, peripheral odontogenic fibroma translation, english dictionary definition of peripheral odontogenic fibroma. Histological features of peripheral odontogenic fibroma is cellular fibrous tissue. Peripheral odontogenic fibroma is an uncommon, benign, unencapsulated, exophytic gingival mass of fibrous connective tissue covered with a surface epithelium. Peripheral odontogenic fibroma definition of peripheral. Kenney jn, kaugars ge, abbey lm 1989 comparison between the peripheral ossifying fibroma and peripheral odontogenic fibroma. Different studies reported high variability in the incidence rate as being between 3 and 23% of all odontogenic tumors 2,3. It develops more commonly on the gum of the lower jaw mandible than the upper jaw maxilla. Dec 01, 2015 odontogenic fibroma of, a rare odontogenic tumor of mesodermal origin, has been thought to originate from either dental follicle, periodontal ligament, or dental papilla 1. A central odontogenic fibroma cof is a rare tumor of odontogenic origin with a diverse histopathology found in both the mandible and the maxilla.
The latter is a reactive lesion, derived from the periosteum and can produce osteoid and woven bone 14. The tumours occurring in the oral cavity may be of odontogenic or nonodontogenic in origin. A 32yearold male patient was referred to the clinic complaining of a localized gingival enlargement of the anterior maxillary region. Peripheral odontogenic fibroma formerly known as fibromatous and ossifying epulis is a benign, often slowgrowing tumor that arises from periodontal structures gums, ligaments, and bone. Peripheral odontogenic tumors are rare neoplasms to occur on gingiva, the most common among them being the peripheral odontogenic fibroma podf. Peripheral odontogenic fibroma pof is a rare odontogenic tumor, characterized by a fibrous or fibromyxomatous proliferation that contains varying amounts of odontogenic or presumed odontogenic epithelium, occasionally with the presence of dentin or cementum like bodies or other forms of calcification. Peripheral odontogenic fibroma pof is a rare benign neoplasm of odontogenic mesenchymal origin that accounts for approximately 4. Lesions diagnosed as peripheral odontogenic fibroma was excluded from the study.
534 878 1110 765 1590 1416 1360 144 906 1285 651 483 1648 413 422 744 648 615 561 874 1533 1052 1495 1576 158 1461 313 797 146 368 13 1616 759 306 347 1596 1106 1531 912 990 331 368 839 662 470 79 388